Venous samples were collected at baseline and at 1, 2, and 5 h postconsumption. Ingestion of blueberries increased plasma levels of reducing and chain-breaking potential (+6.1%, pb0.001; +11.1%, pb0.05) and enhanced plasma concentrations of caffeic and ferulic acid.
The most abundant phenolics in the diet are not necessarily those able to reach the highest levels in human circulation, owing to the considerable differences in bioavailability.
In vivo and in vitro effects of milk addition The in vitro addition of milk to blueberry extracts resulted in a precipitation of blueberry antioxidants, leading to a decrease in TAC
values of the supernatants, with full-fat milk showing the highest degree of inhibition.
The present study suggests, for the first time, that consumption of a fruit rich in antioxidants, such as blueberry, in association with whole milk decreases its ability to increase plasma endogenous antioxidant defenses and to deliver into the circulation bioactive
molecules such as caffeic aci